SMALL BRAINS PREDISPOSED LATE QUATERNARY MAMMALS TO EXTINCTION

Small brains predisposed Late Quaternary mammals to extinction

Abstract The Late Quaternary witnessed a dramatic wave of large mammal extinctions, that are usually attributed to either human hunting or climatic change.We hypothesized that the large mammals that survived the extinctions might have been endowed with larger brain sizes than their relatives, which could have conferred enhanced behavioral plasticit

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Global DNA methylation levels in white blood cells of patients with chronic heroin use disorder. A prospective study

Background: Increasing scientific evidence shows the significant role of epigenetic mechanisms in drug use disorder, abstinence and relapse.Studies on human subjects are limited compared to those on animals, for various reasons such as poly-substance abuse, high drop-out rate and technical difficulties.Objectives: Our goal was to evaluate whether a

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Interactive Movie: A response to Passivity of the Medium

Even Antenna Socket though the film is a passive medium and despite the obstacles of creative, technical and financial nature, experimenting with the interactivity started half a century ago.The audience was gradually enabled to choose alternative outcomes, influence the development of characters, and even co-create the content.This work follows th

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Pseudocell Tracer-A method for inferring dynamic trajectories using scRNAseq and its application to B cells undergoing immunoglobulin class switch recombination.

Single cell RNA sequencing (scRNAseq) can be used to infer a temporal ordering of cellular states.Current methods for the inference of cellular trajectories rely on unbiased dimensionality reduction techniques.However, such biologically agnostic ordering can prove difficult for modeling complex developmental or differentiation processes.The cellula

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BASICS OF PUBLIC SPEAKING

Basics of public speaking is a work in which we emphasize the importance of mastering the techniques of public speaking and oratory skills, in order for that knowledge to serve each individual as a key tool for easier achievement of all objectives of business and personal communication.We Massagers explain and define the very concept of public spea

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